AB1577 EL ÍNDICE DE RESISTENCIA TIENE UNA RELACIÓN ESTRECHA CON LA DESTRUCCIÓN INTRAARTICULAR DE HUESO Y CARTÍLAGO POR DOPPLER ESPECTRAL EN LA ARTRITIS REUMATOIDE

Background Recent reports have shown that high-resolution ultrasound is a useful method of detecting pannus vascularization in inflamed finger joints patients with RA and also assessing the disease activity or monitoring therapeutic responses. Power Doppler ultrasonography (PDUS) techniques not only ability to detect but do depict flow patterns by using spectral analysis. Objectives To evaluate intra-articular metacarpophalangeal (MCP) rheumatoid arthritis (RA) power (PDSUS) technique. The relationship between bone cartilage destruction. Methods Thirty-two (mean age 53.5 ± 13.8) duration 7.8 3.9 years were included into study. Twenty MCP five healthy subjects assessed as controls. Clinical joint inflammation was classified according index for synovitis PD based on swelling, warmness pain. Ultrasonography performed Vinno G86 unit means 6–18 MHz linear array transducer. Gray-scale US sonography examination performed. Using quality determined indices pulsatility (PI) resistance (RI) measured longitudinal plane. erosive scores plain hand radiographs Sharp/van der Heijde method. Results Total 128 32 20 controls examined dominant hand. Flow 30 (10 moderately active, active) eight erosions, whereas twenty-four had no erosions joints. quantifiable flow. Mean PI these control (2.34 0.87), active (1.01 1.1) 0.32 0.6 RI 0.87 0.12 0.61 0.15 (figure 1) 0.24 There significant difference (p <0.01). correlation PI, total (r = 0.40 r 0.41, P < 0.05). Figure 1. Moderately Conclusion Spectral demonstrating synovial offers new alternatives measurement response. intimate References [1]Terslev L, S Torp-Pedersen, E Qvistgaard, B Danneskiold-Samsoe, H Bliddal. Estimation ultrasound: quantitative changes after treatment arthritis. Ann Rheum Dis 2003; 62:1049–1053 [2]Salih Ozgocmen, Adem Kiris, Ercan Kocakoc, Ozge Ardicoglu, Ayhan Kamanli, Evaluation technique: periarticular mineral density, Joint Bone Spine, Volume 71, Issue 5, 2004: 384-388, Acknowledgements: NIL. Disclosure Interests None Declared.